Journal article
Use of 18F-ASEM PET to Determine the Availability of the α7-Nicotinic Acetylcholine Receptor in Recent-Onset Psychosis
Abstract
Limited postmortem evidence suggests a diminished availability of the α7 nicotinic acetylcholine receptor (α7-nAChR) in hippocampus in psychosis. Methods: In this cross-sectional PET study, we used 18F-ASEM, a radiotracer targeting the α7-nAChR, with positron emission tomography to compare the binding of 18F-ASEM in hippocampus between individuals with recent-onset psychosis and healthy controls. Results: Individuals with recent-onset psychosis …
Authors
Coughlin JM; Du Y; Crawford JL; Rubin LH; Azad BB; Lesniak WG; Horti AG; Schretlen DJ; Sawa A; Pomper MG
Journal
Journal of Nuclear Medicine, Vol. 60, No. 2, pp. 241–243
Publisher
Society of Nuclear Medicine
Publication Date
February 2019
DOI
10.2967/jnumed.118.213686
ISSN
0161-5505