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Systematic review and meta-analysis of the safety...
Journal article

Systematic review and meta-analysis of the safety of chloroquine and hydroxychloroquine from randomized controlled trials on malarial and non-malarial conditions

Abstract

BackgroundDespite the expectations regarding the effectiveness of chloroquine (CQ) and hydroxychloroquine (HCQ) for coronavirus disease (COVID-19) management, concerns about their adverse events have remained.ObjectivesThe objective of this systematic review was to evaluate the safety of CQ and HCQ from malarial and non-malarial randomized clinical trials (RCTs).MethodsThe primary outcomes were the frequencies of serious adverse events (SAEs), …

Authors

Souza Botelho M; Bolfi F; Leite RGOF; Leite MSF; Banzato LR; Soares LT; Olivatti TOF; Mangolim AS; Oliveira FRK; Abbade LPF

Journal

Systematic Reviews, Vol. 10, No. 1,

Publisher

Springer Nature

DOI

10.1186/s13643-021-01835-x

ISSN

2046-4053