Sputum cell counts to manage prednisone-dependent asthma: effects on FEV1 and eosinophilic exacerbations

BackgroundPrednisone dependence in asthma is usually described based on clinical and spirometric characteristics. It is generally believed that these patients have frequent exacerbations and lose lung function rapidly because of uncontrolled airway eosinophilia.ObjectivesThe objectives of this study are to report the effect on asthma exacerbations and the change in lung function over time in prednisone-dependent asthma when severe asthma is …