An in vitro assessment of the toxicity of 2,4‐dichloroaniline using rainbow trout primary epidermal cell cultures

Abstract 2,4-Dichloroaniline (2,4-DCA) is a common pollutant of freshwaters. Information on the effects of this chemical on the aquatic environment is lacking. In this work, we present a technique using primary cell culture of rainbow trout (Oncorhynchus mykiss) epidermal cells as a model for the evaluation of the potential ecotoxicologic hazards of 2,4-DCA. The effects of a wide dose range of the chemical on survival and function of the cells …