Journal article
Modification effect of ideal cardiovascular health metrics on genetic association with incident heart failure in the China Kadoorie Biobank and the UK Biobank
Abstract
BackgroundBoth genetic and cardiovascular factors contribute to the risk of developing heart failure (HF), but whether idea cardiovascular health metrics (ICVHMs) offset the genetic association with incident HF remains unclear.ObjectivesTo investigate the genetic association with incident HF as well as the modification effect of ICVHMs on such genetic association in Chinese and British populations.MethodsAn ICVHMs based on smoking, drinking, …
Authors
Yang R; Lv J; Yu C; Guo Y; Pei P; Huang N; Yang L; Millwood IY; Walters RG; Chen Y
Journal
BMC Medicine, Vol. 19, No. 1,
Publisher
Springer Nature
Publication Date
December 2021
DOI
10.1186/s12916-021-02122-1
ISSN
1741-7015