Journal article
No-carrier-added electrochemical nucleophilic radiofluorination of aromatics
Abstract
Direct nucleophilic radiosynthesis of di-tert-butyl-(4-[18F]fluoro-1,2-phenylene)-dicarbonate was conducted through no-carrier-added electrochemical reactions. 10 mM of triethylamine acetic acid (Et3N·3HAc) in acetonitrile was used to release [18F]fluoride ion trapped in the quaternary ammonium anion exchange resin. The relationship between radiofluorination efficiency, concentration of the Et3N·3HAc, and the working potential were studied with …
Authors
He Q; Alfeazi I; Sadeghi S
Journal
Journal of Radioanalytical and Nuclear Chemistry, Vol. 303, No. 1, pp. 1037–1040
Publisher
Springer Nature
Publication Date
January 2015
DOI
10.1007/s10967-014-3604-1
ISSN
0236-5731