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Production of diverse PET probes with limited...
Journal article

Production of diverse PET probes with limited resources: 24 18F-labeled compounds prepared with a single radiosynthesizer

Abstract

New radiolabeled probes for positron-emission tomography (PET) are providing an ever-increasing ability to answer diverse research and clinical questions and to facilitate the discovery, development, and clinical use of drugs in patient care. Despite the high equipment and facility costs to produce PET probes, many radiopharmacies and radiochemistry laboratories use a dedicated radiosynthesizer to produce each probe, even if the equipment is …

Authors

Collins J; Waldmann CM; Drake C; Slavik R; Ha NS; Sergeev M; Lazari M; Shen B; Chin FT; Moore M

Journal

Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, No. 43, pp. 11309–11314

Publisher

Proceedings of the National Academy of Sciences

Publication Date

October 24, 2017

DOI

10.1073/pnas.1710466114

ISSN

0027-8424