The further development of rainbow trout primary epithelial cell cultures as a diagnostic tool in ecotoxicology risk assessment

The use of short-term cytotoxicity assays for the initial screening of chemicals not only aids in establishing priorities for the selection of chemicals that should be tested in vivo, but also decreases the time in which potential toxicants can be valued. Rainbow trout primary skin epithelial cell cultures are one such assay. Rainbow trout primary skin cell cultures contain two cell types, keratinocytes and goblet mucus cells. Two aquatic …