Journal article
Electrochemical Flash Fluorination and Radiofluorination
Abstract
A new method for rapid late-stage fluorination using the cation pool technique is presented. Fluorination and no-carrier-added radiofluorination of methyl (phenylthio) acetate, methyl 2-(methylthio) acetate, and methyl 2-(ethylthio) acetate were performed. The carbocations formed through electrochemical oxidation were stabilized by using a divided electrochemical cell and 2,2,2-trifluoroethanol (TFE) as the solvent at -20 °C. At the end of …
Authors
Balandeh M; Rios A; Allison N; Shirazi D; Gomez A; Rambaran L; Holloway T; Sadeghi S
Journal
ChemElectroChem, Vol. 5, No. 22, pp. 3353–3356
Publisher
Wiley
Publication Date
November 13, 2018
DOI
10.1002/celc.201800973
ISSN
2196-0216