Journal article
The effect of radiation in combination with carcinogens on the growth of normal urothelium in explant culture
Abstract
Radiation is known to be carcinogenic to humans but attempts to demonstrate the process using human tissue culture models have met with little success. In the present study explants were established from urothelium and exposed to radiation and a range of chemical carcinogens, suspected promotor or metabolic agents. The resulting outgrowth was monitored for growth rate, proliferating epithelial fraction and development and differentiation of …
Authors
Mothersill C; O'Brien A; Seymour CB
Journal
Radiation and Environmental Biophysics, Vol. 29, No. 3, pp. 213–223
Publisher
Springer Nature
Publication Date
9 1990
DOI
10.1007/bf01210524
ISSN
0301-634X