Journal article
Relative Contribution of Bystander and Targeted Cell Killing to the Low-Dose Region of the Radiation DoseResponse Curve
Abstract
Human keratinocytes show a bystander effect when exposed to low doses of low-LET radiation. In this paper, data are presented showing a method of correcting the overall survival curve to enable analysis of the relative contributions of the bystander effect and the effect attributable to direct interaction of the radiation with the target cell. The technique used is to obtain a standard clonogenic survival curve using the assay of Puck and …
Authors
Seymour CB; Mothersill C
Journal
Radiation Research, Vol. 153, No. 5, pp. 508–511
Publisher
Radiation Research Society
Publication Date
May 2000
DOI
10.1667/0033-7587(2000)153[0508:rcobat]2.0.co;2
ISSN
0033-7587