Journal article
γ-H2AX as a Marker for Dose Deposition in the Brain of Wistar Rats after Synchrotron Microbeam Radiation
Abstract
OBJECTIVE: Synchrotron radiation has shown high therapeutic potential in small animal models of malignant brain tumours. However, more studies are needed to understand the radiobiological effects caused by the delivery of high doses of spatially fractionated x-rays in tissue. The purpose of this study was to explore the use of the γ-H2AX antibody as a marker for dose deposition in the brain of rats after synchrotron microbeam radiation therapy …
Authors
Fernandez-Palomo C; Mothersill C; Bräuer-Krisch E; Laissue J; Seymour C; Schültke E
Journal
PLOS ONE, Vol. 10, No. 3,
Publisher
Public Library of Science (PLoS)
DOI
10.1371/journal.pone.0119924
ISSN
1932-6203