Journal article
New anticoagulants and the management of their bleeding complications
Abstract
SUMMARY Limitations of the currently available anticoagulants have fanned the continuing search for new anticoagulants with improved pharmacological and biosafety profile, and equal, if not superior efficacy. Targets of inhibition include the factor VIIa/tissue factor pathway (recombinant nematode anticoagulant peptide c2, tissue factor pathway inhibitor), factor Xa (fondaparinux, idraparinux, razaxaban), factor Va and VIIIa pathway …
Authors
NG HJ; CROWTHER M
Journal
Transfusion Alternatives in Transfusion Medicine, Vol. 8, No. s1, pp. 12–19
Publisher
Wiley
Publication Date
12 2006
DOI
10.1111/j.1778-428x.2006.00026.x
ISSN
1295-9022