Journal article
Draft Genome Sequence of Streptomyces silvensis ATCC 53525, a Producer of Novel Hormone Antagonists
Abstract
Streptomyces silvensis produces nonribosomal peptides that act as antagonists of the human oxytocin and vasopressin receptors. Here, we present the genome sequence of S. silvensis ATCC 53525 and demonstrate that this organism possesses a number of additional biosynthetic gene clusters and might be a promising source for genome-guided drug discovery efforts.
Authors
Johnston CW; Li Y; Magarvey NA
Journal
Microbiology Resource Announcements, Vol. 4, No. 1, pp. e00001–e00016
Publisher
American Society for Microbiology
Publication Date
February 25, 2016
DOI
10.1128/genomea.00001-16
ISSN
2169-8287