Journal article
EMT signaling: potential contribution of CRISPR/Cas gene editing
Abstract
Epithelial to mesenchymal transition (EMT) is a complex plastic and reversible cellular process that has critical roles in diverse physiological and pathological phenomena. EMT is involved in embryonic development, organogenesis and tissue repair, as well as in fibrosis, cancer metastasis and drug resistance. In recent years, the ability to edit the genome using the clustered regularly interspaced palindromic repeats (CRISPR) and associated …
Authors
Mohammadinejad R; Biagioni A; Arunkumar G; Shapiro R; Chang K-C; Sedeeq M; Taiyab A; Hashemabadi M; Pardakhty A; Mandegary A
Journal
Cellular and Molecular Life Sciences, Vol. 77, No. 14, pp. 2701–2722
Publisher
Springer Nature
Publication Date
July 2020
DOI
10.1007/s00018-020-03449-3
ISSN
1420-682X