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Age-stratified and blood-pressure-stratified...
Journal article

Age-stratified and blood-pressure-stratified effects of blood-pressure-lowering pharmacotherapy for the prevention of cardiovascular disease and death: an individual participant-level data meta-analysis

Abstract

BACKGROUND: The effects of pharmacological blood-pressure-lowering on cardiovascular outcomes in individuals aged 70 years and older, particularly when blood pressure is not substantially increased, is uncertain. We compared the effects of blood-pressure-lowering treatment on the risk of major cardiovascular events in groups of patients stratified by age and blood pressure at baseline. METHODS: We did a meta-analysis using individual …

Authors

Collaboration TBPLTT; Rahimi K; Bidel Z; Nazarzadeh M; Copland E; Canoy D; Wamil M; Majert J; McManus R; Adler A

Journal

The Lancet, Vol. 398, No. 10305, pp. 1053–1064

Publisher

Elsevier

Publication Date

September 2021

DOI

10.1016/s0140-6736(21)01921-8

ISSN

0140-6736