Journal article
BOND: Basic OligoNucleotide Design
Abstract
BackgroundDNA microarrays have become ubiquitous in biological and medical research. The most difficult problem that needs to be solved is the design of DNA oligonucleotides that (i) are highly specific, that is, bind only to the intended target, (ii) cover the highest possible number of genes, that is, all genes that allow such unique regions, and (iii) are computed fast. None of the existing programs meet all these criteria.ResultsWe …
Authors
Ilie L; Mohamadi H; Golding GB; F Smyth W
Journal
BMC Bioinformatics, Vol. 14, No. 1,
Publisher
Springer Nature
Publication Date
12 2013
DOI
10.1186/1471-2105-14-69
ISSN
1471-2105