Journal article
Pressure and Volume Limited Ventilation for the Ventilatory Management of Patients with Acute Lung Injury: A Systematic Review and Meta-Analysis
Abstract
BACKGROUND: Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are life threatening clinical conditions seen in critically ill patients with diverse underlying illnesses. Lung injury may be perpetuated by ventilation strategies that do not limit lung volumes and airway pressures. We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) comparing pressure and volume-limited (PVL) ventilation …
Authors
Burns KEA; Adhikari NKJ; Slutsky AS; Guyatt GH; Villar J; Zhang H; Zhou Q; Cook DJ; Stewart TE; Meade MO
Journal
PLOS ONE, Vol. 6, No. 1,
Publisher
Public Library of Science (PLoS)
DOI
10.1371/journal.pone.0014623
ISSN
1932-6203