Journal article
The efficacy and safety of plasma exchange in patients with sepsis and septic shock: a systematic review and meta-analysis
Abstract
IntroductionSepsis and septic shock are leading causes of intensive care unit (ICU) mortality. They are characterized by excessive inflammation, upregulation of procoagulant proteins and depletion of natural anticoagulants. Plasma exchange has the potential to improve survival in sepsis by removing inflammatory cytokines and restoring deficient plasma proteins. The objective of this study is to evaluate the efficacy and safety of plasma …
Authors
Rimmer E; Houston BL; Kumar A; Abou-Setta AM; Friesen C; Marshall JC; Rock G; Turgeon AF; Cook DJ; Houston DS
Journal
Critical Care, Vol. 18, No. 6,
Publisher
Springer Nature
Publication Date
January 1, 2014
DOI
10.1186/s13054-014-0699-2
ISSN
1364-8535