Journal article
The yjeQ Gene Is Required for Virulence of Staphylococcus aureus
Abstract
Gene products required for in vivo growth and survival of Staphylococcus aureus and other pathogens represent new targets for antimicrobial chemotherapy. In this study we created a Staphylococcus aureus yjeQ deletion strain and tested its virulence using a mouse kidney abscess infection model. The yjeQ deletion strain was compromised for growth in vitro and severely attenuated for virulence. We concluded that yjeQ is an attractive and novel new …
Authors
Campbell TL; Henderson J; Heinrichs DE; Brown ED
Journal
Infection and Immunity, Vol. 74, No. 8, pp. 4918–4921
Publisher
American Society for Microbiology
Publication Date
August 2006
DOI
10.1128/iai.00258-06
ISSN
0019-9567