Journal article
Probing Teichoic Acid Genetics with Bioactive Molecules Reveals New Interactions among Diverse Processes in Bacterial Cell Wall Biogenesis
Abstract
The bacterial cell wall has been a celebrated target for antibiotics and holds real promise for the discovery of new antibacterial chemical matter. In addition to peptidoglycan, the walls of Gram-positive bacteria contain large amounts of the polymer teichoic acid, covalently attached to peptidoglycan. Recently, wall teichoic acid was shown to be essential to the proper morphology of Bacillus subtilis and an important virulence factor for …
Authors
D'Elia MA; Millar KE; Bhavsar AP; Tomljenovic AM; Hutter B; Schaab C; Moreno-Hagelsieb G; Brown ED
Journal
Cell Chemical Biology, Vol. 16, No. 5, pp. 548–556
Publisher
Elsevier
Publication Date
May 2009
DOI
10.1016/j.chembiol.2009.04.009
ISSN
2451-9456