Vascular viewpoint

Question: What are the effects of celecoxib, a selective COX-2 inhibitor on endothelial function? Population: Fourteen male patients (46-77 years) with severe coronary artery disease and chronic stable angina who did not have a coronary revascularization procedure three months prior to randomization. All patients were on aspirin and statins. Design and methods: Randomized double-blind, placebo-controlled crossover study. All patients received …