Journal article
Lack of Association Between the Trp719Arg Polymorphism in Kinesin-Like Protein-6 and Coronary Artery Disease in 19 Case-Control Studies
Abstract
OBJECTIVES: We sought to replicate the association between the kinesin-like protein 6 (KIF6) Trp719Arg polymorphism (rs20455), and clinical coronary artery disease (CAD).
BACKGROUND: Recent prospective studies suggest that carriers of the 719Arg allele in KIF6 are at increased risk of clinical CAD compared with noncarriers.
Authors
Assimes TL; Hólm H; Kathiresan S; Reilly MP; Thorleifsson G; Voight BF; Erdmann J; Willenborg C; Vaidya D; Xie C
Journal
Journal of the American College of Cardiology, Vol. 56, No. 19, pp. 1552–1563
Publisher
Elsevier
Publication Date
November 2010
DOI
10.1016/j.jacc.2010.06.022
ISSN
0735-1097