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Gene-Centric Meta-Analysis of Lipid Traits in...
Journal article

Gene-Centric Meta-Analysis of Lipid Traits in African, East Asian and Hispanic Populations

Abstract

Meta-analyses of European populations has successfully identified genetic variants in over 100 loci associated with lipid levels, but our knowledge in other ethnicities remains limited. To address this, we performed dense genotyping of ∼2,000 candidate genes in 7,657 African Americans, 1,315 Hispanics and 841 East Asians, using the IBC array, a custom ∼50,000 SNP genotyping array. Meta-analyses confirmed 16 lipid loci previously established in …

Authors

Elbers CC; Guo Y; Tragante V; van Iperen EPA; Lanktree MB; Castillo BA; Chen F; Yanek LR; Wojczynski MK; Li YR

Journal

PLOS ONE, Vol. 7, No. 12,

Publisher

Public Library of Science (PLoS)

Publication Date

2012

DOI

10.1371/journal.pone.0050198

ISSN

1932-6203