A comprehensive 1000 Genomes–based genome-wide...

A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease

Abstract

Hugh Watkins, Sekar Kathiresan, Ruth McPherson, Martin Farrall and colleagues report the results of a large genome-wide association meta-analysis of coronary artery disease based on 1000 Genomes imputation. They identify ten new risk loci and show that susceptibility to this disease is largely determined by common SNPs with small effect sizes.

Authors

Nikpay M; Goel A; Won H-H; Hall LM; Willenborg C; Kanoni S; Saleheen D; Kyriakou T; Nelson CP; Hopewell JC

Journal

Nature Genetics, Vol. 47, No. 10, pp. 1121–1130

Publisher

Springer Nature

Publication Date

September 29, 2015

DOI

10.1038/ng.3396

ISSN

1061-4036

Associated Experts

Sonia Anand

Professor, Faculty of Health Sciences

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