Journal article
Contrasting effects of a classic Nrf2 activator, tert-butylhydroquinone, on the glutathione-related antioxidant defenses in Pacific oysters, Crassostrea gigas
Abstract
Nrf2 is a well-known transcription factor controlling a number of antioxidant defense-related genes, which is understudied in bivalves. In this study, oysters Crassostrea gigas were exposed for 24, 48 and 96 h to 10 or 30 μM tert-butylhydroquinone (tBHQ), a classic Nrf2 activator. At 96 h, a clear induction of GSH-related antioxidant defenses was observed in gills of tBHQ-exposed animals, including GSH, glutathione S-transferase (GST), …
Authors
Danielli NM; Trevisan R; Mello DF; Fischer K; Deconto VS; Bianchini A; Bainy ACD; Dafre AL
Journal
Marine Environmental Research, Vol. 130, , pp. 142–149
Publisher
Elsevier
Publication Date
9 2017
DOI
10.1016/j.marenvres.2017.07.020
ISSN
0141-1136