Journal article
Distribution of Cell-Free and Cell-Associated HIV Surrogates in the Colon After Simulated Receptive Anal Intercourse in Men Who Have Sex With Men
Abstract
OBJECTIVES: Describing the distribution and clearance of HIV surrogates within the gastrointestinal tract to inform rectal microbicide development.
DESIGN: Radiolabeled simulated HIV-infected semen was administered, imaged, and biopsied to simulate and measure colonic HIV distribution after anal intercourse.
Authors
Louissaint NA; Nimmagadda S; Fuchs EJ; Bakshi RP; Cao Y-J; Lee LA; Goldsmith J; Caffo BS; Du Y; King KE
Journal
JAIDS Journal of Acquired Immune Deficiency Syndromes, Vol. 59, No. 1, pp. 10–17
Publisher
Wolters Kluwer
Publication Date
January 1, 2012
DOI
10.1097/qai.0b013e3182373b5e
ISSN
1525-4135