Journal article
PET imaging of soluble epoxide hydrolase in non-human primate brain with [18F]FNDP
Abstract
PurposeSoluble epoxide hydrolase (sEH) is a promising candidate positron emission tomography (PET) imaging biomarker altered in various disorders, including vascular cognitive impairment (VCI), Alzheimer’s disease (AD), Parkinson’s disease (PD), stroke, and depression, known to regulate levels of epoxyeicosatrienoic acids (EETs) and play an important role in neurovascular coupling. [18F]FNDP, a PET radiotracer for imaging sEH, was evaluated …
Authors
Du Y; Minn I; Foss C; Lesniak WG; Hu F; Dannals RF; Pomper MG; Horti AG
Journal
EJNMMI Research, Vol. 10, No. 1,
Publisher
Springer Nature
Publication Date
December 2020
DOI
10.1186/s13550-020-00657-7
ISSN
2191-219X