Journal article
Clinical trials in COVID-19 management & prevention: A meta-epidemiological study examining methodological quality
Abstract
OBJECTIVE: To describe the characteristics of Covid-19 randomized clinical trials (RCTs) and examine the association between trial characteristics and the likelihood of finding a significant effect.
STUDY DESIGN: We conducted a systematic review to identify RCTs (up to October 21, 2020) evaluating drugs or blood products to treat or prevent Covid-19. We extracted trial characteristics (number of centers, funding sources, and sample size) and …
Authors
Honarmand K; Penn J; Agarwal A; Siemieniuk R; Brignardello-Petersen R; Bartoszko JJ; Zeraatkar D; Agoritsas T; Burns K; Fernando SM
Journal
Journal of Clinical Epidemiology, Vol. 139, , pp. 68–79
Publisher
Elsevier
Publication Date
November 2021
DOI
10.1016/j.jclinepi.2021.07.002
ISSN
0895-4356