Journal article
Forty-Three Loci Associated with Plasma Lipoprotein Size, Concentration, and Cholesterol Content in Genome-Wide Analysis
Abstract
While conventional LDL-C, HDL-C, and triglyceride measurements reflect aggregate properties of plasma lipoprotein fractions, NMR-based measurements more accurately reflect lipoprotein particle concentrations according to class (LDL, HDL, and VLDL) and particle size (small, medium, and large). The concentrations of these lipoprotein sub-fractions may be related to risk of cardiovascular disease and related metabolic disorders. We performed a …
Authors
Chasman DI; Paré G; Mora S; Hopewell JC; Peloso G; Clarke R; Cupples LA; Hamsten A; Kathiresan S; Mälarstig A
Journal
PLOS Genetics, Vol. 5, No. 11,
Publisher
Public Library of Science (PLoS)
Publication Date
11 2009
DOI
10.1371/journal.pgen.1000730
ISSN
1553-7390