Journal article
Hundreds of variants clustered in genomic loci and biological pathways affect human height
Abstract
The genetics of human heightA genome-wide association (GWA) study of more than 180,000 individuals has identified hundreds of genetic variants in at least 180 loci associated with adult human height. The loci are not clustered randomly but are enriched for genes involved in growth-related processes that influence adult height. This demonstrates that GWA studies of common human traits, and therefore of many diseases, can identify large numbers …
Authors
Lango Allen H; Estrada K; Lettre G; Berndt SI; Weedon MN; Rivadeneira F; Willer CJ; Jackson AU; Vedantam S; Raychaudhuri S
Journal
Nature, Vol. 467, No. 7317, pp. 832–838
Publisher
Springer Nature
Publication Date
10 2010
DOI
10.1038/nature09410
ISSN
0028-0836