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Association of Variation at the ABO Locus With...
Journal article

Association of Variation at the ABO Locus With Circulating Levels of Soluble Intercellular Adhesion Molecule-1, Soluble P-selectin, and Soluble E-selectin

Abstract

BACKGROUND: Circulating levels of soluble intercellular adhesion molecule-1, soluble P-selectin, and soluble E-selectin have been associated with variation at the ABO locus. To evaluate these associations and the effect sizes, we performed a meta-analysis with new and previous reported data for polymorphism rs579459. METHODS AND RESULTS: Compared with major allele homozygotes, heterozygotes and minor allele homozygotes had 4.6% (95% CI, …

Authors

Kiechl S; Paré G; Barbalic M; Qi L; Dupuis J; Dehghan A; Bis JC; Laxton RC; Xiao Q; Bonora E

Journal

Circulation Genomic and Precision Medicine, Vol. 4, No. 6, pp. 681–686

Publisher

Wolters Kluwer

Publication Date

12 2011

DOI

10.1161/circgenetics.111.960682

ISSN

1942-325X