Journal article
Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease 1 , 2 , 3 , 4 , 5
Abstract
BACKGROUND: The strong observational association between total homocysteine (tHcy) concentrations and risk of coronary artery disease (CAD) and the null associations in the homocysteine-lowering trials have prompted the need to identify genetic variants associated with homocysteine concentrations and risk of CAD.
OBJECTIVE: We tested whether common genetic polymorphisms associated with variation in tHcy are also associated with CAD.
Authors
van Meurs JBJ; Pare G; Schwartz SM; Hazra A; Tanaka T; Vermeulen SH; Cotlarciuc I; Yuan X; Mälarstig A; Bandinelli S
Journal
American Journal of Clinical Nutrition, Vol. 98, No. 3, pp. 668–676
Publisher
Elsevier
Publication Date
September 2013
DOI
10.3945/ajcn.112.044545
ISSN
0002-9165