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Pharmacogenetics in Cardiovascular Disease: The...
Journal article

Pharmacogenetics in Cardiovascular Disease: The Challenge of Moving From Promise to Realization

Abstract

Pharmacogenetics in cardiovascular medicine brings the potential for personalized therapeutic strategies that improve efficacy and reduce harm. Studies evaluating the impact of genetic variation on pharmacologic effects have been undertaken for most major cardiovascular drugs, including antithrombotic agents, β-adrenergic receptor blockers, statins, and angiotensin-converting enzyme inhibitors. Across these drug classes, many polymorphisms …

Authors

Joseph PG; Pare G; Ross S; Roberts R; Anand SS

Journal

Clinical Cardiology, Vol. 37, No. 1, pp. 48–56

Publisher

Wiley

Publication Date

January 2014

DOI

10.1002/clc.22200

ISSN

0160-9289