Journal article
Early Change in Epithelial Neutrophilic Infiltrate Predicts Long-Term Response to Biologics in Ulcerative Colitis
Abstract
BACKGROUND & AIMS: The prognostic value of histologic scores, grades, and individual histologic subcomponents, alone or in combination with endoscopy, for predicting endoscopic improvement (EI) and histoendoscopic mucosal improvement (HEMI) during maintenance therapy in ulcerative colitis remains uncertain.
METHODS: We performed a post hoc analysis of participants from the VARSITY trial (n = 734 with histology). Receiver operating …
Authors
Narula N; Wong ECL; Colombel J-F; Riddell R; Marshall JK; Reinisch W; Dulai PS
Journal
Clinical Gastroenterology and Hepatology, Vol. 20, No. 5, pp. 1095–1104.e9
Publisher
Elsevier
Publication Date
5 2022
DOI
10.1016/j.cgh.2021.07.005
ISSN
1542-3565