Journal article
Quantitative Mass Spectrometric Profiling of Cancer-cell Proteomes Derived From Liquid and Solid Tumors
Abstract
In-depth analyses of cancer cell proteomes are needed to elucidate oncogenic pathomechanisms, as well as to identify potential drug targets and diagnostic biomarkers. However, methods for quantitative proteomic characterization of patient-derived tumors and in particular their cellular subpopulations are largely lacking. Here we describe an experimental set-up that allows quantitative analysis of proteomes of cancer cell subpopulations derived …
Authors
Bohnenberger H; Ströbel P; Mohr S; Corso J; Berg T; Urlaub H; Lenz C; Serve H; Oellerich T
Journal
Journal of Visualized Experiments, , No. 96,
Publisher
MyJove
DOI
10.3791/52435
ISSN
1940-087X