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Saffron Pre-Treatment Promotes Reduction in Tissue...
Journal article

Saffron Pre-Treatment Promotes Reduction in Tissue Inflammatory Profiles and Alters Microbiome Composition in Experimental Colitis Mice

Abstract

Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the gastrointestinal tract with an incompletely understood pathogenesis. Long-standing colitis is associated with increased risk of colon cancer. Despite the availability of various anti-inflammatory and immunomodulatory drugs, many patients fail to respond to pharmacologic therapy and some experience drug-induced adverse events. Dietary supplements, particularly saffron (Cr…

Authors

Banskota S; Brim H; Kwon YH; Singh G; Sinha SR; Wang H; Khan WI; Ashktorab H

Journal

Molecules, Vol. 26, No. 11,

Publisher

MDPI

DOI

10.3390/molecules26113351

ISSN

1431-5157