Towards a non-invasive computational diagnostic framework for personalized cardiology of transcatheter aortic valve replacement in interactions with complex valvular, ventricular and vascular disease

Aortic stenosis is an acute and chronic cardiovascular disease that often coexists with other complex valvular, ventricular and vascular diseases (C3VD). Transcatheter aortic valve replacement is an emerging less invasive intervention for patients with aortic stenosis. Although hemodynamics quantification is critical for accurate and early diagnosis of aortic stenosis and C3VD, proper diagnostic methods for these diseases are still lacking …