Journal article
Memory Generation and Re-Activation in Food Allergy
Abstract
Recent evidence has highlighted the critical role of memory cells in maintaining lifelong food allergies, thereby identifying these cells as therapeutic targets. IgG+ memory B cells replenish pools of IgE-secreting cells upon allergen exposure, which contract thereafter due to the short lifespan of tightly regulated IgE-expressing cells. Advances in the detection and highly dimensional analysis of allergen-specific B and T cells from allergic …
Authors
Koenig JFE; Bruton K; Phelps A; Grydziuszko E; Jiménez-Saiz R; Jordana M
Journal
ImmunoTargets and Therapy, Vol. 10, No. 0, pp. 171–184
Publisher
Taylor & Francis
Publication Date
June 9, 2021
DOI
10.2147/itt.s284823
ISSN
2253-1556