Journal article
Characterization and localization of the Gova/b alloantigens to the glycosylphosphatidylinositol-anchored protein CDw109 on human platelets
Abstract
The Gova/b alloantigens are expressed on a 175-kD protein (GP175) on human platelets. Anti-Gov alloantibodies have been implicated in posttransfusion purpura and alloimmune neonatal thrombocytopenia. In this report we characterize the immunochemistry of the alloantigens and identify the platelet protein that expresses the Gov epitopes. Approximately 50% of GP175 containing the Gov epitope was released from platelets treated with …
Authors
Smith J; Hayward C; Horsewood P; Warkentin T; Denomme G; Kelton J
Journal
Blood, Vol. 86, No. 7, pp. 2807–2814
Publisher
American Society of Hematology
Publication Date
October 1, 1995
DOI
10.1182/blood.v86.7.2807.bloodjournal8672807
ISSN
0006-4971