Chapter
Abstracts
Abstract
Expression of an activated raf transgene accelerated the terminal myeloid differentiation of HL-60 human promyelocytic leukemia cells induced by retinoic acid. A similar result was obtained when 1,25-dihydroxy vitamin D3 was used to induce monocytic differentiation. The stable transfectants were derived by transfecting HL-60 cells with DNA encoding an N-terminal truncated raf-1 protein. In normal HL-60 cells retinoic acid is known to induce a …
Authors
Yen A; Williams M; Platko JD; Der C; Hisaka M; Feigin AM; Wang C; Stiles CD; Cavalcanti TC; Guimaraesr F
Book title
Diet and Cancer
Series
Advances in Experimental Medicine and Biology
Volume
354
Pagination
pp. 157-218
Publisher
Springer Nature
Publication Date
1995
DOI
10.1007/978-1-4899-0949-7_14