Symptomatic knee osteoarthritis is associated with worse but stable quality of life and physical function regardless of the compartmental involvement: Data from the OAI

Objective: To test whether combined patellofemoral and tibiofemoral osteoarthritis (OA), in addition to symptoms, is associated with greater changes in quality of life and objective physical function measures when compared with asymptomatic isolated tibiofemoral osteoarthritis. Design: Of the 4796 participants in the Osteoarthritis Initiative, 577 were categorized into four groups based on the presence of symptoms (asymptomatic and symptomatic) …