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The Z-Profile Study: a multicenter, retrospective...
Journal article

The Z-Profile Study: a multicenter, retrospective cohort study to assess the real-world use and effectiveness of elbasvir/grazoprevir in Canadian adult patients with chronic hepatitis C

Abstract

Background: Canada was the first country to approve elbasvir/grazoprevir (EBR/GZR) for the treatment of chronic HCV infection for genotypes 1 and 4 with or without ribavirin and genotype 3 with sofosbuvir, with no recommendation for baseline resistance testing. The aim of this study was to describe the effectiveness of EBR/GZR and the profile of patients selected for treatment in a Canadian real-world setting. Methods: This multicenter …

Authors

Tam E; Tremblay J; Fraser C; Conway B; Ramji A; Borgia S; Tsoi K; Yoshida EM; Rajendran B; Macphail G

Journal

Canadian Liver Journal, Vol. 3, No. 3, pp. 251–262

Publisher

University of Toronto Press

Publication Date

August 2020

DOI

10.3138/canlivj-2019-0029

ISSN

2561-4444

Labels

Sustainable Development Goals (SDG)