t‐Butyl 2‐Chloro‐2‐trimethylsilylacetate

[66406‐43‐7] C9H19ClO2Si (MW 222.79) [66406‐43‐7] C9H19ClO2Si (MW 222.79) InChI = 1S/C9H19ClO2Si/c1‐9(2,3)12‐8(11)7(10)13(4,5)6/h7H,1‐6H3 InChIKey = REVBFXGFKCMPSR‐UHFFFAOYSA‐N (alkenation of enolizable ketones leading to functionalized, tetrasubstituted alkenes (α,β‐unsaturated esters) via a Peterson alkenation) Physical Data: bp 55 °C/1.4 mmHg. Solubility: sol THF. Preparative Method: prepared from t-Butyl Chloroacetate by sequential reaction with Lithium Diisopropylamide and Chlorotrimethylsilane followed by aqueous workup and distillation. Handling, Storage, and Precautions: as this material is an activated alkyl halide, it must be considered a potential alkylating agent and lachrymator and handled with care and suitable protective clothing (e.g. gloves) in a fume hood.