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A274 GUT MICROBIOTA REGULATES INNATE EPITHELIAL...
Journal article

A274 GUT MICROBIOTA REGULATES INNATE EPITHELIAL RESPONSES AGAINST AN ENTERIC BACTERIAL PATHOGEN

Abstract

Our gut microbiota plays a protective role in the GI tract, by promoting colonization resistance against enteric pathogens through nutrient competition. Antibiotic treatments in early life can lead to prolonged microbial dysbiosis and increase susceptibility to future enteric infections. Moreover, the gut microbiota have been shown to impact the development of the mucosal and systemic immune systems. Intestinal epithelial cells (IEC) are …

Authors

Allaire JM; Yang H; Moore N; Crowley SM; Verdu E; Vallance B

Journal

Journal of the Canadian Association of Gastroenterology, Vol. 1, No. suppl_2, pp. 396–396

Publisher

Oxford University Press (OUP)

Publication Date

March 1, 2018

DOI

10.1093/jcag/gwy009.274

ISSN

2515-2084