Journal article
ALeS: adaptive-length spaced-seed design
Abstract
MOTIVATION: Sequence similarity is the most frequently used procedure in biological research, as proved by the widely used BLAST program. The consecutive seed used by BLAST can be dramatically improved by considering multiple spaced seeds. Finding the best seeds is a hard problem and much effort went into developing heuristic algorithms and software for designing highly sensitive spaced seeds.
RESULTS: We introduce a new algorithm and software, …
Authors
Mallik A; Ilie L
Journal
Bioinformatics, Vol. 37, No. 9, pp. 1206–1210
Publisher
Oxford University Press (OUP)
Publication Date
June 9, 2021
DOI
10.1093/bioinformatics/btaa945
ISSN
1367-4803