Chapter
Analysis of Anti-Interferon Properties of the Herpes Simplex Virus Type I ICP0 Protein
Abstract
A defining hallmark of the type 1 interferons (IFNs) is their ability to interfere with virus replication. As such, viruses have evolved diverse mechanisms to subvert the antiviral effects of interferons. Herpes simplex virus type 1 (HSV-1) is a large deoxyribonucleic acid virus best known for its ability to cause cold sores in infected individuals. In cultured cells, HSV-1 is relatively resistant to the effects of IFNs. Plaque reduction assays …
Authors
Mossman K
Book title
Interferon Methods and Protocols
Volume
116
Pagination
pp. 195-205
Publisher
Springer Nature
Publication Date
2005
DOI
10.1385/1-59259-939-7:195