Journal article
Terminal half‐life of FVIII and FIX according to age, blood group and concentrate type: Data from the WAPPS database
Abstract
BACKGROUND: Real-life data on pharmacokinetics of factor (F) VIII/IX concentrates, especially extended half-life (EHL), concentrates in large cohorts of persons with hemophilia are currently lacking.
OBJECTIVES: This cross-sectional study aimed to establish reference values for terminal half-life (THL) for FVIII/IX concentrates according to concentrate type, age, blood group and inhibitor history.
Authors
Versloot O; Iserman E; Chelle P; Germini F; Edginton AN; Schutgens REG; Iorio A; Fischer K; Group TPEWGOTIPS
Journal
Journal of Thrombosis and Haemostasis, Vol. 19, No. 8, pp. 1896–1906
Publisher
Elsevier
Publication Date
8 2021
DOI
10.1111/jth.15395
ISSN
1538-7933