Journal article
Comparative effectiveness of higher adalimumab maintenance therapy versus standard dose in anti‐tumor necrosis factor experienced Crohn's disease patients: A propensity‐score matched cohort analysis
Abstract
BACKGROUND AND AIM: Crohn's disease (CD) patients who previously failed anti-tumor necrosis factor (TNF) therapy are at higher risk of treatment failure with subsequent biologics. This study aims to determine the effectiveness and safety of higher maintenance dose regimens of adalimumab compared with standard doses in CD patients who failed anti-TNF.
METHODS: In this retrospective observational study, CD patients who failed anti-TNF and …
Authors
Narula N; Wong ECL; AlRamdan R; Bualbanat H; Marshall JK; Steinhart AH; Greener T; Silverberg MS
Journal
Journal of Gastroenterology and Hepatology, Vol. 36, No. 10, pp. 2803–2812
Publisher
Wiley
Publication Date
October 2021
DOI
10.1111/jgh.15551
ISSN
0815-9319