Journal article
Polymer-free corticosteroid dimer implants for controlled and sustained drug delivery
Abstract
Polymeric drug carriers are widely used for providing temporal and/or spatial control of drug delivery, with corticosteroids being one class of drugs that have benefitted from their use for the treatment of inflammatory-mediated conditions. However, these polymer-based systems often have limited drug-loading capacity, suboptimal release kinetics, and/or promote adverse inflammatory responses. This manuscript investigates and describes a …
Authors
Battiston K; Parrag I; Statham M; Louka D; Fischer H; Mackey G; Daley A; Gu F; Baldwin E; Yang B
Journal
Nature Communications, Vol. 12, No. 1,
Publisher
Springer Nature
DOI
10.1038/s41467-021-23232-7
ISSN
2041-1723